ATP5B Antibody

Size

100ug

Clone Number

Aliases

ATP 5B antibody; ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide antibody; ATP synthase subunit beta mitochondrial antibody; ATP synthase subunit beta; mitochondrial antibody; atp5b antibody; ATPB antibody; ATPB_HUMAN antibody; ATPMB antibody; ATPSB antibody; Epididymis secretory protein Li 271 antibody; HEL-S-271 antibody; Mitochondrial ATP synthase beta subunit antibody; Mitochondrial ATP Synthase Subunit Beta antibody; Mitochondrial ATP synthetase beta subunit antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P06576

Immunogen

Recombinant Human ATP synthase subunit beta, mitochondrial protein (230-529AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ATP5B

Research Areas

Cancer; Tags & Cell Markers; Metabolism; Signal transduction