ATL2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules| including a propeptide region| a metalloproteinase domain| a disintegrin-like domain| and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs| and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain| and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human ATL2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

ATL2; ADAMTS-like protein 2; ADAMTSL-2