ATF1 Antibody

Size

100ul

Clone Number

Aliases

Activating transcription factor 1 antibody; ATF 1 antibody; atf1 antibody; ATF1 EWS fusion gene antibody; ATF1 FUS fusion gene antibody; ATF1_HUMAN antibody; cAMP dependent transcription factor 1 antibody; cAMP-dependent transcription factor ATF-1 antibody; Cyclic AMP dependent transcription factor ATF 1 antibody; Cyclic AMP dependent transcription factor ATF1 antibody; Cyclic AMP-dependent transcription factor ATF-1 antibody; EWS AFT1 antibody; FUS ATF 1 antibody; FUS/ATF 1 antibody; Protein TREB36 antibody; RNA binding protein activating transcription factor 1 fusion protein antibody; TREB 36 antibody; TREB36 antibody; TREB36 protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P18846

Immunogen

Recombinant Human Cyclic AMP-dependent transcription factor ATF-1 protein (1-210AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background

This protein binds the cAMP response element (CRE) (consensus: 5\\\'-GTGACGT[AC][AG]-3\\\'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ATF1

Research Areas

Epigenetics and Nuclear Signaling