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ABCbiolab

SKU:ABCCS50564

ASTN2 Antibody

ASTN2 Antibody

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Size

100ug

Clone Number

Aliases

Astn2 antibody; ASTN2_HUMAN antibody; Astrotactin 2 antibody; Astrotactin-2 antibody; bA264C15.1 antibody; bA67K19.1 antibody; KIAA0634 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75129

Immunogen

Recombinant Human Astrotactin-2 protein (108-272AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ASTN2

Research Areas

Neuroscience

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