ASPC1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether| which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin| and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human ASPC1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

60830

synonyms

ASPC1