ascl1a Antibody

Size

100ug

Clone Number

Aliases

ascl1a antibody; ash antibody; ash1a antibody; asha antibody; piaAchaete-scute homolog 1a antibody; Zash-1a antibody; Pituitary-absent protein antibody

Immunogen Species

Danio rerio (Zebrafish) (Brachydanio rerio)

UniProt ID

Q90259

Immunogen

Recombinant Zebrafish Achaete-scute homolog 1a protein (1-196AA)

Raised in

Rabbit

Species Reactivity

Zebrafish

Tested Applications

ELISA

Background

Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (By similarity). Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ascl1a

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience