ASCL1 Antibody

Size

100ug

Clone Number

Aliases

Achaete scute complex homolog 1 antibody; Achaete scute complex homolog like 1 antibody; Achaete scute complex homologue 1 antibody; Achaete scute complex homologue like 1 antibody; Achaete scute complex like 1 antibody; Achaete scute family bHLH transcription factor 1 antibody; Achaete scute protein antibody; Achaete-scute homolog 1 antibody; Ascl 1 antibody; ascl1 antibody; ASCL1_HUMAN antibody; Ash 1 antibody; ASH-1 antibody; Ash1 antibody; bHLHa46 antibody; Class A basic helix-loop-helix protein 46 antibody; Hash 1 antibody; HASH1 antibody; Mammalian achaete scute homolog 1 antibody; Mammalian achaete scute homologue 1 antibody; Mash 1 antibody; Mash1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P50553

Immunogen

Recombinant Human Achaete-scute homolog 1 protein (1-236AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5\\\'-CANNTG-3\\\'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ASCL1

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience