AS3MT Antibody

Size

100ug

Clone Number

Aliases

2310045H08Rik antibody; Arsenic (+3 oxidation state) methyltransferase antibody; Arsenite methyltransferase antibody; As3mt antibody; AS3MT_HUMAN antibody; C10ORF32 antibody; CYT19 antibody; Cyt19 protein antibody; Hypothetical protein C10orf32 antibody; Methylarsonite methyltransferase antibody; Methyltransferase cyt19 antibody; OTTHUMP00000020384 antibody; RP11-753C18.6 antibody; S adenosylmethionine arsenic (III) methyltransferase antibody; S-adenosyl-L-methionine:arsenic(III) methyltransferase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HBK9

Immunogen

Recombinant Human Arsenite methyltransferase protein (262-375AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

AS3MT

Research Areas

Cell biology; Metabolism; Signal transduction