ARPP19 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

ARP19 antibody; ARP19_HUMAN antibody; ARPP-19 antibody; Arpp19 antibody; cAMP-regulated phosphoprotein 19 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P56211

Immunogen

Recombinant Human cAMP-regulated phosphoprotein 19 protein (2-105AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ARPP19

Research Areas

Cell biology; Signal transduction