ARHGEF10 Polyclonal Antibody

Ab type

Primary antibody

Background

ARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.

Reactivity

Human;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

151612

synonyms

ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10