ARHGAP22 Polyclonal Antibody

Ab type

Primary antibody

Background

ARHGAP22 (Rho GTPase activating protein 22) encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for ARHGAP22.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human RHG22. AA range:565-614

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

76779

synonyms

ARHGAP22; RHOGAP2; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22