Arginase II Polyclonal Antibody

Ab type

Primary antibody

Background

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ARG2. AA range:305-354

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

38578

synonyms

ARG2; Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase