ARFGAP1 Antibody

Size

100ul

Clone Number

Aliases

ADP ribosylation factor 1 GTPase activating protein antibody; ADP ribosylation factor GTPase activating protein 1 antibody; ADP-ribosylation factor 1 GTPase-activating protein antibody; ADP-ribosylation factor GTPase-activating protein 1 antibody; ARF GAP 1 antibody; ARF1 directed GTPase activating protein antibody; ARF1 GAP antibody; ARF1-directed GTPase-activating protein antibody; ARF1GAP antibody; ARFG1_HUMAN antibody; Arfgap1 antibody; GAP protein antibody; HRIHFB2281 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N6T3

Immunogen

Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 protein (1-220AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle\\\'s fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine .

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ARFGAP1

Research Areas

Signal transduction