ARF6 Antibody

Size

100ul

Clone Number

Aliases

ADP ribosylation factor 6 antibody; ADP ribosylation factor protein 6 antibody; ADP-ribosylation factor 6 antibody; ARF6 antibody; ARF6_HUMAN antibody; DKFZp564M0264 antibody; Small GTP binding protein antibody; Small GTPase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P62330

Immunogen

Recombinant Human ADP-ribosylation factor 6 protein (1-175AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background

GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ARF6

Research Areas

Signal transduction