AQP4 Polyclonal Antibody

Ab type

Primary antibody

Background

AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein (aquaporin 4) is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human AQP4. AA range:204-253

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

34830

synonyms

AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4