APP-BP2 Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by APPBP2 (amyloid beta precursor protein binding protein 2) interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. APPBP2 has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from APP-BP2 . at AA range: 390-470

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

66853

synonyms

APPBP2; KIAA0228; PAT1; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1