APOBEC3G Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

A3G antibody; ABC3G_HUMAN antibody; APOBEC related cytidine deaminase antibody; APOBEC related protein antibody; APOBEC-related cytidine deaminase antibody; APOBEC-related protein 9 antibody; APOBEC-related protein antibody; APOBEC3G antibody; Apolipoprotein B editing enzyme catalytic polypeptide like 3G antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G antibody; Apolipoprotein B mRNA editing enzyme catalytic subunit 3G antibody; apolipoprotein B mRNA editing enzyme cytidine deaminase antibody; apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like antibody; ARCD antibody; ARP-9 antibody; ARP9 antibody; bK150C2.7 antibody; CEM-15 antibody; CEM15 antibody; deoxycytidine deaminase antibody; dJ494G10.1 antibody; DNA dC dU editing enzyme APOBEC 3G antibody; DNA dC->dU editing enzyme antibody; DNA dC->dU-editing enzyme APOBEC-3G antibody; EC 3.5.4. antibody; FLJ12740 antibody; MDS019 antibody; OTTHUMP00000028911 antibody; phorbolin-like protein antibody; phorbolin-like protein MDS019 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HC16

Immunogen

Recombinant Human DNA dC->dU-editing enzyme APOBEC-3G protein (1-384AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

APOBEC3G

Research Areas

Epigenetics and Nuclear Signaling; Immunology; Microbiology