APOA5 Antibody

Size

100ug

Clone Number

Aliases

Apo-AV antibody; ApoA-V antibody; Apoa5 antibody; APOA5_HUMAN antibody; ApoAV antibody; Apolipoprotein A-V antibody; Apolipoprotein A5 antibody; RAP3 antibody; Regeneration associated protein 3 antibody; Regeneration-associated protein 3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6Q788

Immunogen

Recombinant Human Apolipoprotein A-V protein (260-366AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

APOA5

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction