APLP-1 Polyclonal Antibody

Ab type

Primary antibody

Background

APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid-like protein 1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from APLP-1 . at AA range: 360-440

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

72176

synonyms

APLP1; Amyloid-like protein 1; APLP; APLP-1