APIP Antibody

Size

100ul

Clone Number

Aliases

Apaf1 Interacting Protein antibody; APAF1-interacting protein antibody; APIP antibody; APIP2 antibody; CG129 antibody; CGI 29 antibody; CGI29 antibody; dJ179L10.2 antibody; MMRP19 antibody; Monocyte/macrophage protein 19 antibody; MTNB_HUMAN antibody; MTRu 1 P dehydratase antibody; MTRu-1-P dehydratase antibody; Probable methylthioribulose 1 phosphate dehydratase antibody; Probable methylthioribulose-1-phosphate dehydratase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96GX9

Immunogen

Recombinant Human Methylthioribulose-1-phosphate dehydratase protein (1-242AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

APIP

Research Areas

Cell biology