API5 Antibody

Size

100ug

Clone Number

Aliases

AAC 11 antibody; AAC-11 antibody; AAC11 antibody; Antiapoptosis clone 11 protein antibody; API 5 antibody; API-5 antibody; api5 antibody; API5 like 1 antibody; API5_HUMAN antibody; API5L1 antibody; Apoptosis inhibitor 5 antibody; Cell migration inducing gene 8 protein antibody; Cell migration-inducing gene 8 protein antibody; Fibroblast growth factor 2 interacting factor 2 antibody; Fibroblast growth factor 2-interacting factor antibody; FIF antibody; MIG 8 antibody; MIG8 antibody; Migration inducing protein MIG8 antibody; Protein XAGL antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BZZ5

Immunogen

Recombinant Human Apoptosis inhibitor 5 protein (396-524AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

API5

Research Areas

Cancer; Cell biology