APH1B Antibody

Size

100ul

Clone Number

Aliases

Anterior pharynx defective 1 homolog B (C. elegans) antibody; Anterior pharynx defective 1 homolog B antibody; Anterior pharynx defective 1B like antibody; Anterior pharynx defective 1b short splicing variant antibody; APH 1B antibody; Aph 1beta antibody; APH-1b antibody; Aph-1beta antibody; Aph1 beta antibody; aph1b antibody; APH1B_HUMAN antibody; Aph1beta antibody; DKFZp564D0372 antibody; Gamma secretase subunit APH 1B antibody; Gamma secretase subunit APH1B antibody; Gamma secretase sununit antibody; Gamma-secretase subunit Aph-1b antibody; Presenilin stabilisation factor like antibody; Presenilin-stabilization factor-like antibody; PRO 1328 antibody; PRO1328 antibody; PSFL antibody; TAAV 688 antibody; TAAV688 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WW43

Immunogen

Peptide sequence from Human Gamma-secretase subunit APH-1B protein (93-110AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

APH1B

Research Areas

Neuroscience