AP2B Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome| suggesting that this gene functions in the differentiation of neural crest cell derivatives.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human AP2B

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

50600

synonyms

AP2B