anti- SMAD3 antibody

Host

Rabbit

Uniprot ID

P84022

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Immunogen

SMAD family member 3

Synonyms

MADH3, hMAD 3, hSMAD3, HSPC193, HsT17436, JV15 2, MAD homolog 3, Mad3, Mothers against DPP homolog 3, SMAD 3, SMAD family member 3, SMAD3

Observed MW

48 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID

4088

Research Area

Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Cancer, Developmental biology, Stem Cells