ABCbiolab
SKU:ABCF07778
anti- SLC27A2 antibody
anti- SLC27A2 antibody
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Host
Rabbit
Uniprot ID
O14975
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen
solute carrier family 27 (fatty acid transporter), member 2
Synonyms
ACSVL1, FACVL1, FATP2, VLACS
Observed MW
70 kDa
Reactivity
Human, Mouse
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Gene ID
11001
Research Area
Signal Transduction
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