anti- SH3BP1 antibody

Host

Rabbit

Uniprot ID

Q9Y3L3

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac(By similarity).

Immunogen

SH3-domain binding protein 1

Synonyms

Observed MW

76-80 kDa,51 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID

23616

Research Area

Signal Transduction