anti- SETDB2 antibody

Host

Rabbit

Uniprot ID

Q96T68

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3(H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1(CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

Immunogen

SET domain, bifurcated 2

Synonyms

C13orf4, CLLD8, KMT1F

Observed MW

101 kDa

Reactivity

Human

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

83852

Research Area

Epigenetics, Metabolism