anti- SEPT7 antibody

Host

Rabbit

Uniprot ID

Q16181

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Immunogen

septin 7

Synonyms

CDC10, CDC10 protein homolog, CDC3, Nbla02942, SEPT7, SEPT7A, septin 7

Observed MW

51 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, IF, WB

Recommended dilution

WB: 1:1000 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Gene ID

989

Research Area

Cell Division and Proliferation