anti- SEC61alpha antibody

Host

Rabbit

Uniprot ID

P61619

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

The SEC61 complex is a major component of the endoplasmic reticulum(ER) translocation site(PMID: 7720858). This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER.

Immunogen

Sec61 alpha 1 subunit(S. cerevisiae)

Synonyms

FLJ10578, Sec61 alpha 2, SEC61A, SEC61A2, SEC61alpha

Observed MW

52 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF

Recommended dilution

WB: 1:200-1:2000; IF: 1:10-1:100

Gene ID

Research Area

Signal Transduction