anti- SEC14L1 antibody

Host

Rabbit

Uniprot ID

Q92503

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation(PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters(PubMed:17092608).

Immunogen

SEC14-like 1(S. cerevisiae)

Synonyms

SEC14L

Observed MW

81 kDa, 77 kDa

Reactivity

Human

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

6397

Research Area

Metabolism