anti- SCD antibody

Host

Rabbit

Uniprot ID

O00767

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates(PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids(PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation(By similarity). Plays an important role in body energy homeostasis(By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides(By similarity).

Immunogen

stearoyl-CoA desaturase(delta-9-desaturase)

Synonyms

Observed MW

Reactivity

Human

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:20-1:200

Gene ID

6319

Research Area

Metabolism