anti- SAMHD1 antibody

Host

Rabbit

Uniprot ID

Q9Y3Z3

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.

Immunogen

SAM domain and HD domain 1

Synonyms

MOP5

Observed MW

64-72 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP, FC

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID

25939

Research Area

Immunology, Metabolism