anti- SAE1 antibody

Host

Rabbit

Uniprot ID

Q9UBE0

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Immunogen

SUMO1 activating enzyme subunit 1

Synonyms

AOS1, SUA1, UBLE1A

Observed MW

38 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

10055

Research Area

Epigenetics, Metabolism