ABCbiolab
SKU:ABCF07230
anti- RP2 antibody
anti- RP2 antibody
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Host
Rabbit
Uniprot ID
O75695
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Acts as a GTPase-activating protein(GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119(or UNC119B). Acts as a GTPase-activating protein(GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
Immunogen
retinitis pigmentosa 2
Synonyms
DELXp11.3, KIAA0215, Protein XRP2, RP2, TBCCD2
Observed MW
40 kDa
Reactivity
Human, Mouse, Rat
Tested Application
ELISA, WB, IHC, FC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Gene ID
6102
Research Area
Neuroscience, Metabolism
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