anti- ROBO3 antibody

Host

Rabbit

Uniprot ID

Q96MS0

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1(By similarity). Required for hindbrain axon midline crossing.

Immunogen

roundabout, axon guidance receptor, homolog 3(Drosophila)

Synonyms

Observed MW

55 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID

64221

Research Area

Neuroscience, Stem Cells, Cardiovascular, Developmental biology