anti- RNASEH1 antibody

Host

Rabbit

Uniprot ID

O60930

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids(PubMed:10497183). Plays a role in RNA polymerase II(RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II(PubMed:21700224).

Immunogen

ribonuclease H1

Synonyms

RNH1

Observed MW

32 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Gene ID

246243

Research Area

Metabolism