anti- RMI1 antibody

Host

Rabbit

Uniprot ID

Q9H9A7

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions(DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

Immunogen

RMI1, RecQ mediated genome instability 1, homolog(S. cerevisiae)

Synonyms

C9orf76

Observed MW

75 kDa

Reactivity

Human

Tested Application

ELISA, IHC, IP, WB

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID

80010

Research Area

Metabolism