anti- RGS7 antibody

Host

Rabbit

Uniprot ID

P49802

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity(PubMed:10521509). May play a role in synaptic vesicle exocytosis(PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling(PubMed:15897264).

Immunogen

regulator of G-protein signaling 7

Synonyms

Observed MW

62 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID

6000

Research Area

Signal Transduction