anti- RGS2 antibody

Host

Rabbit

Uniprot ID

P41220

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:11063746, PubMed:19478087). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle(By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein(PubMed:19736320).

Immunogen

regulator of G-protein signaling 2, 24kDa

Synonyms

G0S8, RGS2

Observed MW

24kd

Reactivity

Human

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Gene ID

5997

Research Area

Signal Transduction