anti- RECK antibody

Host

Rabbit

Uniprot ID

O95980

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Negatively regulates matrix metalloproteinase-9(MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

Immunogen

reversion-inducing-cysteine-rich protein with kazal motifs

Synonyms

RECK, ST15, reversion-inducing cysteine-rich protein with Kazal motifs

Observed MW

110 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

8434

Research Area

Cell Division and Proliferation, cancer