anti- RCC1 antibody

Host

Rabbit

Uniprot ID

P18754

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex(together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Immunogen

regulator of chromosome condensation 1

Synonyms

CHC1

Observed MW

50 kDa

Reactivity

Human, Mouse, Rat, Monkey

Tested Application

ELISA, WB, IHC, IP, IF

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

1104

Research Area

Cancer, Cell Division and Proliferation, Metabolism