anti- RCC1 antibody

Host

Rabbit

Uniprot ID

P18754

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.

Immunogen

regulator of chromosome condensation 1

Synonyms

Cell cycle regulatory protein, CHC1, RCC1, RCC1 I

Observed MW

50 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP, IF

Recommended dilution

WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

1104

Research Area

Cancer, Cell Division and Proliferation, Metabolism