anti- RBPMS antibody

Host

Rabbit

Uniprot ID

Q93062

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).

Immunogen

RNA binding protein with multiple splicing

Synonyms

HERMES

Observed MW

28-30 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF, FC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

11030

Research Area

Metabolism