anti- RBM15 antibody

Host

Mouse

Uniprot ID

Q96T37

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

6B1

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.

Immunogen

RNA binding motif protein 15

Synonyms

FLJ12479, FLJ21943, One twenty two protein 1, OTT, OTT1, RBM15, RNA binding motif protein 15, SPEN

Observed MW

107 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC, IF, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:200-1:800; IF: 1:10-1:100

Gene ID

64783

Research Area

Stem Cells