anti- RARB antibody

Host

Rabbit

Uniprot ID

P10826

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements(RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Immunogen

retinoic acid receptor, beta

Synonyms

HAP, NR1B2

Observed MW

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, IF

Recommended dilution

IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

5915

Research Area

Cancer, Signal Transduction, Metabolism, Developmental biology