ABCbiolab
SKU:ABCF06963
anti- RAPSN antibody
anti- RAPSN antibody
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Host
Rabbit
Uniprot ID
Q13702
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen
receptor-associated protein of the synapse
Synonyms
RNF205
Observed MW
43 kDa
Reactivity
Human, Mouse, Rat
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Gene ID
5913
Research Area
Neuroscience
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