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ABCbiolab

SKU:ABCF06963

anti- RAPSN antibody

anti- RAPSN antibody

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size
Host
Uniprot ID

Host

Rabbit

Uniprot ID

Q13702

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

as determined by SDS-PAGE

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

receptor-associated protein of the synapse

Synonyms

RNF205

Observed MW

43 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Gene ID

5913

Research Area

Neuroscience

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