anti- RANBP9 antibody

Host

Rabbit

Uniprot ID

Q96S59

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA(By similarity).

Immunogen

RAN binding protein 9

Synonyms

RANBPM

Observed MW

80-90 kDa

Reactivity

Human, Mouse, Rat, Dog

Tested Application

ELISA, IHC, WB, IF

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

10048

Research Area

Metabolism