anti- RAC2 antibody

Host

Mouse

Uniprot ID

P15153

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

8F0

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species(ROS) by NADPH oxidase.

Immunogen

ras-related C3 botulinum toxin substrate 2(rho family, small GTP binding protein Rac2)

Synonyms

EN 7, Gx, HSPC022, p21 Rac2, RAC2, Small G protein

Observed MW

21 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:2000-1:10000; IHC: 1:20-1:200

Gene ID

5880

Research Area

Signal Transduction