anti- RAB32 antibody

Host

Rabbit

Uniprot ID

Q13637

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission(PubMed:12186851). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis(PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis(PubMed:23084991). In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes(By similarity).

Immunogen

RAB32, member RAS oncogene family

Synonyms

Observed MW

28 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID

10981

Research Area

Signal Transduction