anti- RAB12 antibody

Host

Rabbit

Uniprot ID

Q6IQ22

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy(By similarity).

Immunogen

RAB12, member RAS oncogene family

Synonyms

RAB12, Ras related protein Rab 12

Observed MW

28 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC, IP, IF

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:50-1:500

Gene ID

201475

Research Area

Signal Transduction